嬰兒微生物群研究
Tiny Health 與 Free to Feed 合作研究嬰兒微生物群
精準微生物組平台 Tiny Health 與嬰兒餵養倡議組織 Free to Feed，於《Frontiers in Microbiomes》期刊發表一項研究，揭示患有濕疹或食物過敏的嬰兒，其腸道微生物組早於六個月大時，已開始與健康同齡嬰兒出現分歧。
Tiny Health x Free to Feed 的研究分析了 97 名年齡介乎 40 至 46 個月幼兒的糞便樣本，發現雖然過敏及非過敏嬰兒的腸道微生物組在六個月大之前大致相似，但顯著差異會於嬰兒中期階段開始浮現。這些差異可能一直持續至幼兒階段，特徵包括微生物多樣性較低、成熟延遲、抗生素抗藥性標記增加、有益的丁酸鹽生成菌水平降低，以及與發炎相關的微生物豐度較高，凸顯出在生命最早幾個月採取預防性介入的迫切性。
此研究建基於 Tiny Health 先前一項隨機對照試驗的成果之上——該試驗證實，在出生後首數月提供個人化腸道健康支援，可將剖腹產嬰兒出現濕疹的機率降低 83%。
英文原文
The precision microbiome platform Tiny Health and the infant feeding advocacy organization Free to Feed have published a study in Frontiers in Microbiomes that reveals the gut microbiomes of infants with eczema or food allergies begin to diverge from those of healthy peers as early as six months of age.
The Tiny Health x Free to Feed research analyzed stool samples from 97 children aged 40 to 46 months and found that while the microbiomes of allergic and non-allergic infants appear largely similar before six months, meaningful distinctions emerge during mid-infancy. These differences have the ability to persist through toddlerhood and are characterized by lower microbial diversity, delayed maturation, increased antibiotic resistance signatures, reduced levels of beneficial butyrate-producing bacteria, and higher abundance of inflammation-associated microbes. This underscores the urgency of preventive interventions in the earliest months of life.
The study builds on Tiny Health's previous randomized controlled trial, which demonstrated that personalized gut health support in the first months of life reduced eczema odds in cesarean-section babies by 83%.
- 來源
- Trend Hunter
- 發布
- 2026-07-07
- 品類
- Babies
- 出處
- globenewswire